Wim Declercq Selected Research

Caspase 14

3/2013	Caspase-14-deficient mice are more prone to the development of parakeratosis.
12/2012	Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis.
2/2008	Caspase-14 reveals its secrets.
11/2004	Stratum corneum-derived caspase-14 is catalytically active.

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Wim Declercq Research Topics

Disease

18	Inflammation (Inflammations) 01/2022 - 06/2004
11	Neoplasms (Cancer) 01/2020 - 12/2009
10	Necrosis 12/2021 - 02/2003
4	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020 - 11/2004
3	Atopic Dermatitis (Atopic Eczema) 01/2020 - 12/2012
3	Carcinogenesis 11/2019 - 01/2017
2	Asthma (Bronchial Asthma) 01/2020 - 01/2018
2	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 11/2019 - 12/2011
2	Shock 11/2019 - 02/2014
2	Experimental Melanoma 08/2019 - 08/2003
2	Hyperplasia 01/2018 - 04/2009
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 01/2017
2	Infections 07/2015 - 03/2010
2	Sepsis (Septicemia) 02/2014 - 12/2011
2	Netherton Syndrome 09/2009 - 04/2009
1	Skin Diseases (Skin Disease) 01/2020
1	Wounds and Injuries (Trauma) 11/2019
1	Cytokine Release Syndrome 11/2019
1	Hypothermia 11/2019
1	Bronchial Hyperreactivity 01/2018
1	Eosinophilia 01/2018
1	Pterygium 01/2018
1	Blister (Bulla) 12/2017
1	Pemphigus (Pemphigus Vulgaris) 12/2017
1	Cholangiocarcinoma 01/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Leprosy (Hansen's Disease) 07/2015
1	MYD88 Deficiency 09/2014
1	Carcinoma (Carcinomatosis) 09/2014
1	Colorectal Neoplasms (Colorectal Cancer) 09/2014
1	Septic Shock (Toxic Shock Syndrome) 02/2014
1	Dermatitis 03/2013
1	Parakeratosis 03/2013

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2003
9	CaspasesIBA 01/2020 - 06/2004
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2019 - 02/2003
6	Phosphotransferases (Kinase)IBA 11/2019 - 02/2003
4	Filaggrin ProteinsIBA 01/2020 - 02/2008
4	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 09/2014 - 11/2005
4	Caspase 14IBA 03/2013 - 11/2004
3	Caspase 3 (Caspase-3)IBA 12/2021 - 12/2017
3	Serine Proteases (Serine Protease)IBA 01/2020 - 09/2009
3	CytokinesIBA 12/2019 - 01/2019
3	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 04/2006
2	Peptides (Polypeptides)IBA 01/2020 - 12/2019
2	Interleukin-33IBA 01/2020 - 01/2018
2	Protein Kinases (Protein Kinase)IBA 01/2020 - 01/2018
2	Caspase 8 (Caspase-8)IBA 09/2014 - 02/2003
2	NF-kappa B (NF-kB)IBA 05/2010 - 06/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2010 - 06/2007
2	Aspartic Acid (Aspartate)FDA Link 02/2008 - 04/2006
2	p38 Mitogen-Activated Protein KinasesIBA 12/2004 - 06/2004
2	geldanamycinIBA 02/2004 - 02/2003
1	GlucocorticoidsIBA 01/2022
1	Dextrans (Dextran)FDA Link 12/2021
1	CalreticulinIBA 01/2020
1	InterferonsIBA 01/2020
1	AllergensIBA 01/2020
1	Nucleic AcidsIBA 01/2020
1	AntigensIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 12/2019
1	EndonucleasesIBA 12/2019
1	HMGB1 Protein (HMG1)IBA 11/2019
1	TAT-Gap19 peptideIBA 11/2019
1	Connexin 43 (Connexin43)IBA 11/2019
1	fluorescein isothiocyanate bovine serum albuminIBA 08/2019
1	ChemokinesIBA 01/2019
1	Cysteine Proteases (Cysteine Protease)IBA 01/2019
1	benzotropoloneIBA 01/2019
1	Immunoglobulin E (IgE)IBA 01/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2017
1	Immunosuppressive Agents (Immunosuppressants)IBA 12/2017
1	ChromatinIBA 01/2017
1	anthraceneIBA 01/2017
1	UAMC-2526IBA 01/2017
1	Chloroquine (Aralen)FDA LinkGeneric 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Neoplasm Antigens (Tumor Antigens)IBA 04/2016
1	Vitamin D FDA LinkGeneric 07/2015
1	CathelicidinsIBA 07/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 09/2014
1	Carrier Proteins (Binding Protein)IBA 09/2014
1	Interleukin-1 (Interleukin 1)IBA 02/2014
1	Interleukin-18 (Interleukin 18)IBA 02/2014
1	Imiquimod (Aldara)FDA LinkGeneric 03/2013
1	AcidsIBA 03/2010
1	CalciumIBA 03/2010
1	NADP (NADPH)IBA 03/2010
1	Oxidoreductases (Dehydrogenase)IBA 03/2010
1	Phospholipases (Phospholipase)IBA 03/2010
1	LipoxygenasesIBA 03/2010

Therapy/Procedure

3	Therapeutics 01/2017 - 07/2015
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2017
2	Ligation 02/2014 - 12/2011
2	Punctures 02/2014 - 12/2011
1	Intravenous Injections 11/2019
1	Immunotherapy 08/2019